Recombinant Mouse FLVC1 Protein
| Catalog Number： | GXP50206 |
|---|---|
| Swiss Prot： | B2RXV4 |
| Species： | Mouse |
| Expression System： | E. Coli / 293F |
| Sequence： | 1–560aa |
| Tag： | Customize |
| Purity： | >90% |
| Endotoxin： | < 1.0 EU/μg / < 0.1 EU/μg |
Price：¥2580
Delivery Time：3-4周/weeks
Specifications：
Manual：
Product Details
| Product Name： | Recombinant Mouse FLVC1 Protein |
|---|---|
| Synonyms： | Flvcr1 Mfsd7b |
| Catalog Number： | GXP50206 |
| Swiss Prot： | B2RXV4 |
| Species： | Mouse |
| Expression System： | E. Coli / 293F |
| Sequence： | 1–560aa |
| Tag： | Customize |
| Purity： | >90% |
| SDS Page： | Depends On Tags |
| Endotoxin： | < 1.0 EU/μg / < 0.1 EU/μg |
| Carrier Free： | Yes |
| Animal Free： | Yes |
| Formulation： | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| 描述： | Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis (PubMed:37100056). Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids (By similarity). Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane (By similarity). Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment (PubMed:18258918, PubMed:23187127). {ECO:0000250|UniProtKB:Q9Y5Y0, ECO:0000269|PubMed:18258918, ECO:0000269|PubMed:23187127, ECO:0000269|PubMed:37100056}.; [Isoform 1]: Uniporter that mediates the transport of extracellular choline and ethanolamine into cells (By similarity). Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids (By similarity). Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane (By similarity). Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment (PubMed:18258918, PubMed:23187127). Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity (By similarity). Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythropoiesis, a process in which heme synthesis intensifies (By similarity). Possibly export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway (By similarity). Does not export bilirubin. The molecular mechanism of heme transport, whether electrogenic, electroneutral or coupled to other ions, remains to be elucidated (By similarity). {ECO:0000250|UniProtKB:Q9Y5Y0, ECO:0000269|PubMed:18258918, ECO:0000269|PubMed:23187127}.; [Isoform 2]: Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation. {ECO:0000269|PubMed:23187127}. |
| Activity： | Not Test |
| Reconstitution： |
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. 收到重组蛋白产品之后请检查蛋白冻干粉末是否贴于瓶底，如果粉末浮起，开盖之前请先低温离心。将蛋白用说明书中指定的缓冲液复溶至0.1-0.5 mg/mL（请注意蛋白复溶浓度不能低于0.1 mg/mL），室温平衡5-10 min保证充分溶解，复溶过程中请不要剧烈涡旋及吹打蛋白溶液。如需长期储存，建议复溶时添加载体蛋白或者稳定剂（如0.1% BSA, 5% HSA, 10% FBS 或者 5% 海藻糖），同时将复溶后的蛋白溶液按照需求进行分装，储存于-20°C至-80°C，随取随用，避免反复冻融。 |
| Storage： |
Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. 未开盖的干粉蛋白在 -20°C至-80°C可保存12个月； 复溶之后，蛋白溶液在-20°C及以下可保存3个月，在2-8℃可保存1周。 |
