
Cadherin-3 蛋白通过以同亲方式选择性结合其他钙粘蛋白分子来介导细胞间相互作用。这促进了细胞之间的粘附,有助于不同细胞类型的分类和组织。Cadherin-3 还与 CDCP1 和 CTNNB1 相互作用,调节细胞过程和信号通路。
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商品编号: GX00872 库存: 100支
上市时间: 2025-08-22 09:05:10 浏览次数: 935次
研究方向
Cadherin-3 蛋白是一种钙依赖性细胞粘附分子,在介导细胞间相互作用中发挥着至关重要的作用。通过以同种方式选择性地与同类型的其他钙粘蛋白分子相互作用的能力,Cadherin-3 促进连接细胞之间的粘附,从而有助于组织和器官中异质细胞类型的分类和组织。此外,Cadherin-3 与 CDCP1 和 CTNNB1 相互作用,进一步调节细胞过程和信号通路。
Sequence Information
Species:Rat
Gene ID:116777
Swiss Prot:F1LMI3
Synonyms:F1LMI3
Residues:Ser565-Asp822
SPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGN REQLTMIRATVCDCHGQVLNDCPRPWKGGFILPVLGAVLALLTLLLALLLLVRK KRKVKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRND VAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGS DAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD
Product Information
Source: Recombinant expression.
Host: E.coli
Tags: N-terminal His and GST Tag
Subcellular Location: Cell membrane.
Purity: >95%
Traits: Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 .
Original Concentration: 200µg/mL
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point: 4.3
Predicted Molecular Mass: 53.7kDa
Accurate Molecular Mass: 54kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[ IDENTIFICATION ]
Figure 1. SDS-PAGE
[ IMPORTANT NOTE ]
The kit is designed for in vitro and research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.