Recombinant Mouse SCN7A Protein
| Catalog Number： | GXP50179 |
|---|---|
| Swiss Prot： | B1AYL1 |
| Species： | Mouse |
| Expression System： | E. Coli / 293F |
| Sequence： | 1–1681aa |
| Tag： | Customize |
| Purity： | >90% |
| Endotoxin： | < 1.0 EU/μg / < 0.1 EU/μg |
Price：¥2580
Delivery Time：3-4周/weeks
Specifications：
Manual：
Product Details
| Product Name： | Recombinant Mouse SCN7A Protein |
|---|---|
| Synonyms： | Scn7a Nag Nav2 scl11 |
| Catalog Number： | GXP50179 |
| Swiss Prot： | B1AYL1 |
| Species： | Mouse |
| Expression System： | E. Coli / 293F |
| Sequence： | 1–1681aa |
| Tag： | Customize |
| Purity： | >90% |
| SDS Page： | Depends On Tags |
| Endotoxin： | < 1.0 EU/μg / < 0.1 EU/μg |
| Carrier Free： | Yes |
| Animal Free： | Yes |
| Formulation： | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| 描述： | Sodium leak channel functioning as an osmosensor regulating sodium ion levels in various tissues and organs. While most sodium channels are voltage-gated, SCN7A is not and lets sodium flow through membrane along its concentration gradient (PubMed:11027237, PubMed:11992118, PubMed:17408578, PubMed:27252474). In glial cells of the central nervous system, senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake through activation of nearby neurons to maintain appropriate sodium levels in the body (PubMed:11027237, PubMed:17408578, PubMed:27252474). By mediating sodium influx into keratinocytes, also plays a role in skin barrier homeostasis (By similarity). {ECO:0000250|UniProtKB:Q01118, ECO:0000269|PubMed:11027237, ECO:0000269|PubMed:11992118, ECO:0000269|PubMed:17408578, ECO:0000269|PubMed:27252474}. |
| Activity： | Not Test |
| Reconstitution： |
Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. 收到重组蛋白产品之后请检查蛋白冻干粉末是否贴于瓶底，如果粉末浮起，开盖之前请先低温离心。将蛋白用说明书中指定的缓冲液复溶至0.1-0.5 mg/mL（请注意蛋白复溶浓度不能低于0.1 mg/mL），室温平衡5-10 min保证充分溶解，复溶过程中请不要剧烈涡旋及吹打蛋白溶液。如需长期储存，建议复溶时添加载体蛋白或者稳定剂（如0.1% BSA, 5% HSA, 10% FBS 或者 5% 海藻糖），同时将复溶后的蛋白溶液按照需求进行分装，储存于-20°C至-80°C，随取随用，避免反复冻融。 |
| Storage： |
Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. 未开盖的干粉蛋白在 -20°C至-80°C可保存12个月； 复溶之后，蛋白溶液在-20°C及以下可保存3个月，在2-8℃可保存1周。 |
